Oscillatory glucose flux in INS 1 pancreatic β cells: A self-referencing microbiosensor study
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چکیده
منابع مشابه
Oscillatory glucose flux in INS 1 pancreatic β cells: a self-referencing microbiosensor study.
Signaling and insulin secretion in β cells have been reported to demonstrate oscillatory modes, with abnormal oscillations associated with type 2 diabetes. We investigated cellular glucose influx in β cells with a self-referencing (SR) microbiosensor based on nanomaterials with enhanced performance. Dose-response analyses with glucose and metabolic inhibition studies were used to study oscillat...
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Glucose is the central molecule in many biochemical pathways, and numerous approaches have been developed for fabricating micro biosensors designed to measure glucose concentration in/near cells and/or tissues. An inherent problem for microsensors used in physiological studies is a low signal-to-noise ratio, which is further complicated by concentration drift due to the metabolic activity of ce...
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ژورنال
عنوان ژورنال: Analytical Biochemistry
سال: 2011
ISSN: 0003-2697
DOI: 10.1016/j.ab.2010.12.019